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Probiotics for Asthma

Living with asthma is a constant daily challenge for many people. Globally, over 339 million people suffer from asthma. Around 80% of asthma-related death occurs in countries with low or lower-middle-income. According to recent studies, imbalances in the gut microbiota play a critical role in asthma.


The basics of asthma


Asthma is a chronic inflammatory condition that affects the tube that carries air in and out of the lungs. In asthma, your airways narrow and swell and produce extra mucus, making breathing difficult. It also triggers coughing, shortness of breath and whistling sounds as you breathe out.


Asthma may seem minor that require little to no treatment at all. However, for some people, asthma can be a major problem as it can interfere with their daily activities. It can even result in a life-threatening asthma attack.

 There is no cure for asthma, but symptoms can be controlled, especially among kids. However, symptoms of asthma often change over time. So, you must know how to manage asthma. Work with your doctor and keep track of the signs and symptoms.



The gut microbiome of asthmatics


The gut microbiome of people with asthma differs from someone without asthma.


  • The “hygiene hypothesis” suggests that the microbial composition of the gut may play a role in the recent rise in allergic diseases. Early exposure to probiotics can be beneficial for the developing immune system and reduce allergic disease risk, including asthma. Because gut bacteria are known to interact with the immune system, there is some possibility that early probiotic exposure may reduce that risk.
  • In a 2018 study, researchers found that the gut of asthmatic people has prevalent Clostridium and Eggerthella lenta than those who do not have asthma.
  • Children with decreased Bifidobacterium, Faecalibacterium, and Akkermansia are more likely to develop asthma and allergies.
  • The presence of difficile in the gut at 1 month of age is linked with asthma at age 6 to 7.
  • The microbial diversity of those with weight asthma is low during their early childhood.
  • Another study found that formula-fed infants had lower microbial diversity than breastfed infants.


The role of probiotics in asthma


Imbalances in the gut microbiome have been linked to an increased risk and severity of asthma. According to a new study, altering the gut microbiota through probiotic supplementation could make asthma prevention and treatment possible.

In clinical studies, L. rhamnosus, L. casei, B. breve, B. infantis Rosell-33, and B. bifidum Rosell-71 can potentially prevent and treat asthma. Despite this, research shows that probiotics have varying effects on asthmatics as each probiotic strain is unique and different even on the closely related strain. Lactobacillus strain can specifically reduce the severity of asthma and improve asthma control.

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